I prefer running on asphalt roads generally. The main reason is that where I live, the neighborhoods are more mature, and the sidewalks are uneven. I’ve taken two spills on sidewalks in low light and have bruised myself up pretty well. On the road, I get a much more consistent surface and grade. I also don’t constantly dip for every driveway cutout like I do on the sidewalks. Or have to duck for trees that are improperly trimmed. This is all very helpful if you run fast and for real distance. Sure if you are half ass jogging a mile around the neighborhood it doesn’t matter as much.
As for driving, I personally haven’t see it be an issue. You’d have to be driving way too fast and recklessly for this to pose any real inconvenience or safety hazard.