Depression. If you could pick a root cause, what would it be

Physical injury to the brain and body compounded by and compounded with emotional deterioration, to the point of no distinction. Pre adolescent roots of it are deep and difficult to separate from self. Shame turns any insights or progress into commentary to the effect that by having them I am too late, too dumb, and too sensitive to matter, anyway ("idiot"). Weariness in body and spirit reminds me to quit. Repeat.