Let's say a member of your party has contracted Lycanthropy.

Now the current phase of the moon is something that mattered, when up to that point there was no reason to describe or track it.

Now, if your players were attacked by Lycanthropes because it was a full moon and the Lycanthropes were rampaging that question's answered immediately.

But if the Lycanthropes in question are intentionally using their hybrid\animal forms to attack you at any other time, how do you decide how long your player has to get cured before they go feral?