What to expect after first shot

I'd just point out that people tend to post here when they have problems. We rarely get 'hey it was fine and working already' posts.

It also depends on whether you get multiple loading doses, which depends on your condition and doctors. 160mg over a day or two is more likely to trigger something than 40mg every fortnight - maintenance dose. Or if you've taken and failed any other anti-TNFAlpha drugs, like infliximab - Remicade.

Tiredness, (me: brain fog, outright crappiness) after the injection is common so many of us inject in the evening when we don't have anything planned the next day or two. Other folk have little to no side effects.