Tenpines Bluff in FO4 shows no signs of being the site of nuclear incident and shares no similarities to Mars Bluff other than the "bluff" part of the name, which is a common geographical term. I don't think there is any relation whatsoever.
I've never heard of the term "bluff" outside of FO4, and the description on the sign reminded me of the couple and ruins of the house at Tenpines.
Tenpines Bluff in FO4 shows no signs of being the site of nuclear incident and shares no similarities to Mars Bluff other than the "bluff" part of the name, which is a common geographical term. I don't think there is any relation whatsoever.