First successful transplant of pig heart into human received by David Bennett Sr, Maryland
ImageHe just woke up from anesthesia from his heart transplant from Wish and Joe Biden is snapping a selfie with him. The look on his face is appropriate for the moment.
Joe is trying to smell his bacon scent
Joe is trying to remember what bacon smells like
Joe wishes to harvest the pig essence
KALI-MA
KALI-MA
KALI-MA
KAMALA
If he doesn’t smell you he doesn’t like you.
Don't even say that, it will be on Hannity and Carlson tonight and would turn this into a "Biden is turning us into animals" or some shit like that.
I am frankly offended that you would insinuate such great bastions of truth and reporting would distort facts. It's fair and balanced news. Says it right in the title.
Take my free award you magnificent bastard.
I just imagine he wakes up and starts squealing like a pig
You never woke up from anesthesia? You feel COMPLETE SHIT
Not to mention having your chest ripped open and your ribs prayed apart, he’s gonna be laid up for a month, open heart surgery is no joke much less a transplant.
Looks like he just found out he got a pig heart.
He's part pig now
Sweet! Sign me up for a horse dong transplant!
Literal leg transplant
They call me The Tripod
Www
Is a pig heart similar enough to a human heart that this method would be viable in the long run?
Title is wrong, well ot leaves put a very important fact: te pig is genetically modified (which is even more insane, imo). https://www.google.com/amp/s/www.bbc.com/news/world-us-canada-59944889.amp
The pig used in the transplant had been genetically modified to knock out several genes that would have led to the organ being rejected by Mr Bennett's body, the AFP news agency reports.
That's pretty amazing!
He's still going to have to take anti-rejection drugs (immunosuppressants).
Wish all the best for him as this is a ground-breaking procedure.
Dong
Why a pig though?
Pig hearts are fairly similar to human hearts, for example transplants of pig valves have been around for ages.
My father had this surgery at the University of Washington. Experimental, waited for a pig valve large enough. No more heart problems after. Two open heart surgeries previously. Family history of fatal heart attacks, one of which was despite a healthy lifestyle. He passed (was 85) two years ago due to complications from minor strokes. Stepfather passed in 1976 having battled enlarged heart problems for years. We have come along way. Great to see the progress!
Why a pig though?
But seriously its right in the article: Pig hearts are anatomically similar to human hearts but, understandably, not identical. It's not ideal, compared to swapping in a human donor heart. But it is possible to plumb them in and get them working.
I wonder how I managed to miss that bit while reading the article… thanks
Why male models?
Mr Hands has entered the chat
Oh god
HA!
More like a third leg transplant
You’ve made me crying😁😁😁
Bruv 😂😂
Medicine is fucking wild. Doctors and researchers really are on a different level.
Doctors and researchers really are on a different level
You mean they dont drink their own urine??
This made me belly laugh
Elaborate. I’m amused but I want to belly laugh with you
People are drinking their urine to cure their COVID
I didn’t even know. JFC these people
I hope the pig is going to be okay.
Narrator: it will not.
I read it with Sir David Attenborough’s voice
I read it with Jeremy Clarkson's voice
Pats own belly.
It got the human’s heart so don’t worry
No animals were harmed during the process.
Seasoning will be key
How is that possible??? Is a pig heart similar enough to a human heart that this method would be viable in the long run?
The internal organs are quite similar, researchers regularly use pigs as model organisms to study human disease. The problem with pig-human transplantation is that there is a sugar on the surface of pig cells that human immune systems recognize as foreign and cause the body to quickly reject the transplant in a matter of days.
This pig heart comes from a genetically modified pig where the genes for that sugar have been removed. The doctor who performed the surgery prepared by doing 50 pig to baboon heart transplants, and some of those have survived for more than 6 months.
This transplant was given compassionate use authorization because the patient was ineligible for a human heart transplant and would surely die without one soon.
As for the heart transplant, “He realizes the magnitude of what was done and he really realizes the importance of it,” David Bennett Jr. said. “He could not live, or he could last a day, or he could last a couple of days. I mean, we’re in the unknown at this point.”
some of those have survived for more than 6 months.
Lets hope that my man has more time that than baboon
I believe the previous record for a non-human animal to human transplant is a baboon heart into a baby that lasted 21 days.
Is he still alive? Curious how long he lived.
Yo chill, this news just broke like a few hours ago lmao
Let's be optimistic 🙏
I didn’t realize it was so recent 🙈
We are literally in the unknown right now, no one knows.
Curious how long he lived.
How is babby formed?
Sugar on the surface of pig cells? Thank goodness I saw this comment before my next grocery store run for tea and cake supplies. Just gonna go to the butcher’s instead.
I have no idea if it’s sweet like table sugar.
Galactose-alpha-1,3-galactose, commonly known as alpha gal and the Galili antigen, is a carbohydrate found in most mammalian cell membranes. It is not found in primates, including humans, who have lost the GGTA1 gene. Their immune systems recognize it as a foreign body and produce xenoreactive immunoglobulin M antibodies, leading to organ rejection after transplantation.
https://en.m.wikipedia.org/wiki/Galactose-alpha-1,3-galactose
It depends, some humans have similar DNA linked to pigs... like my ex-girlfriend for instance.
This little piggy broke his heart
comedy golden
Also bananas, imagine getting a transplant from a banana.
Slippery slope
Ouch.
I'm honestly jealous of your pfp and username combo. Literal perfection.
It’s good innit?!
Its delightfully tacky!
Kermit the frog? Is that you?
"I dont always eat bacon, but when I do I tell her to wash first"
-BrockHard253
I guess its from one of those pigs genetically modified for this. They experimented on growing human organs in pigs specially for this. Some might say its against the nature and im sure there is allready a religious protest at this hospitals dors, but im glad it worked. That could save soooo many lives
I haven’t put a lot of thoughts on this. But if we have animals for food, why is it bad to have animals to harvest organs? Are they suffering? If not I think it’s like a pretty similar thing.
Nothing is against nature . Nature made us to be able to think , so whatever we do is on nature ,lol
Well that's why "it's natural/not" is a logical fallacy. Being natural isn't inherently good. Being unnatural isn't inherently bad.
I can only agree with you on that, most of those who say its against nature are the same ones that thinks someallmighty guy in the sky watches over us
Lmao ez clap
It's not true. This heart is not modified in it's function. It is an average pig heart. Genetic modifications only removed some genes to get rid of some proteins that are attacked by human immune system.
The person you're replying to stated that this was a genetically modified pig heart. Then you reply saying "it's not true" and then you say it's genetically modified.
Yes It is similar. Not similar as monkey anatomy but it still works. Organs of monkey cannot be used due to ethical concerns. So that pig is a farm animal and its meat is used widely, heart of a pig is a better option for transplant.
Other than the whole heart some times valves inside pigs heart can be seperated and used to replace human cardiac valves.
Main concern would be chronic rejection of the tissue as a result of chronic immune response of hosts body. That problem can be controlled by the use of anti immune drugs such as steroids.
Until we improve tissue engineering and produce native organs with artificial methods we have to use porcine organs and tissues.
All the healthcare workers including doctors respect animals used for scientific studies or medical purpose. That is why term "sacrified" is used for animals instead of "killed".
What exactly is the ethical concern against using monkey organs? Seeing they killed 50 baboons to test this and I've, unfortunately, seen what else they test on monkeys before...
Believe it or not, you have to get permission from ethical comittee to do transplant procedure.
Some giant cosmetic company maybe killed 50 baboons but that is nothing to do with modern medicine. Im talking about science and medicine.
You cannot find a single drug or surgical study that is done on baboons or monkeys unless it is a veterinarian study.
Another commenter said the doctor did 50 pig to baboon transplants to practice
I know about ethic committees all too well. Like how killing a dog after food testing is more humane than operating under general anaesthesia to check their intestines (even though the dog is fine after the operation and can be adopted out)...
Also, the 50 baboons were killed for this procedure to be possible, not for cosmetics.
Oh, and here in NL it's not allowed to use animals for cosmetic testing since 2009.
And what do you mean you can't find any study done on baboons or monkeys? They're even used in testing for corona. Plenty of studies done on them. Shamed to say the biggest test facility for monkeys is in the Netherlands :(
It's because it's not a pig heart, I mean it's not exactly the same hearth you can find in a butcher shop, it has human DNA and has been created on purpose throughout several procedures, so it's hard to say it's a "pig heart", it's more like a human hearth based on a pig heart, of course it sound less spectacular, but complex.
"HONEY BOO-BOO! WHAT'RE YOU GONNA TELL THEM JUDGES WHEN THEY ASK ABOUT YOUR PIG HEART?" "MY HEART'S SWEETER THAN BACON, CHILD! "
That was rhe first thing that came through my mind after seeing this.
South park predicting the future again, lmao
We’re off the Simpson timeline and straight into the South Park one
I want that 'un! He looked at me funny!
Literally the first thing i though of
Taking the selfie like “ayo lemme get a photo real quick, Reddit’s gonna love this”
Gotta get proof that he lived before the pig heart takes a piss.
We consider this person still human, right? How many body parts do we have to replace to make him a pig? Or could we put a human brain in a pig, will that make it a human? If so, must the pig be able to talk of is acting like a pig sufficient? I am confused.
Ship of Theseus
Pig of Theseus
The pig which is own by thesis slowly gets replaces theseus’s body parts, when does the pig become thesus(yes like among us), farther more if all the parts of thesus were re arranged into Theseus would the second Theseus be Theseus?
I like how you spelt theseus three different ways
im very good at english
When it becomes over 50% it's a pig, under it's a human. In between 50% human pig
So weird to see this same reference come up two days in a row. I think Reddit may just be a hive mind.
Lol it’s like the if I have an old axe, then replace the handle, then replace the head, is it still the same axe? I like these sort of lateral thinking puzzles, but it’s definitely crazier to be talking about an actual person ha
Wait I thought we were doing this already? Was I wrong?
You're somewhat correct. They were only using heart valves from pigs before. This time they transplanted the full heart.
Aha!! Thank you! That makes sense!
So cool!
Hol up. So heart failure isn't going to be a thing anymore? Somebody pass me the bacon poutine!
You might not wanna get ahead of yourself there bud
There will lots of left over hearts with all the bacon consumed ;)
Big man pig man
I would be so uncomfortable knowing I have a pig heart and not a human heart inside me. Anyone else? My OCD is kicking in
I mean in this scenario you would be dead without it so how uncomfortable would you really be in that casket?
Edit…
Well I guess you wouldn’t be comfy or uncomfortable you would be straight up neutral!
But chaotic neutral, lawful neutral or true neutral?
what about neutral neutral
Then you chose dying and save the pigs heart for someone else. Good for you
I would more comfortable knowing an animal lost its life (especially since I eat meat) and I gained a heart rather than I received a heart due to a tragedy that someone’s family will never really heal from
To live means to cause suffering.
I thoink it would get to me.
I see what you did there
Would it help thinking/knowing that you have more microorganisms living in and on you than you have human cells?
https://www.sciencefocus.com/the-human-body/human-microbiome/
The company edited out three genes in the pig’s DNA that would’ve caused a human body to reject the organ, while adding in six human genes that would cause the heart to be accepted.
It's grown in a pig, but in a sense not really a pig heart any more.
Are you actually being serious?
How do you know if you have a human or pig heart now? Does it feel human to you? What would a pig heart feel like?
Fascinating questions, we live in great times.
I would much prefer a kosher heart transplant.
He looks about as happy as he can be
Some would dare to say “happy as a pig”
Okay, this guy is already old, but how do they solve the problem, that a pig is only getting 15-20 years old? Are you getting a new heart every few years when you have a heart transplant in younger years?
For people with end-stage heart failure, a heart transplant is considered the "gold standard" treatment. A new study suggests that living for 15 to 20 years after a heart transplant is becoming the rule rather than the exception.
It would be as good as a human heart transplant if it lasted 15-20 years.
Human heart transplants only last a finite time anyway
Do pigs usually die from Heart Failure?
Mostly butchers, I don’t think that’s a problem for humans
Until the automatic butcher system detects your pig heart🐖
I'm old enough to remember the first heart transplant and the first mechanical heart transplant.
Hope the pigs doing ok with tha human heart.
Does this mean a pig was genetically modified, raised, then killed to provide the heart for this man? Curious what vegans think of this
"Veganism is a philosophy and way of living which seeks to exclude—as far as is possible and practicable—all forms of exploitation of, and cruelty to, animals for food, clothing or any other purpose; and by extension, promotes the development and use of animal-free alternatives for the benefit of animals, humans and the environment. In dietary terms it denotes the practice of dispensing with all products derived wholly or partly from animals."
Emphasis added.
Basically, medical use is usually considered necessary (as opposed to cosmetics testing, for example), but general consensus I'd argue (we're an extremely diverse bunch. It is a broad ideology, after all, not a religion) is we should be pushing research towards cruelty free options as we move forward. Necessary evils might not have to be permanent as long as we don't settle here and call it "good enough". So I'd hope that while this is what we have for now, research for something that's kind towards all life and also doesn't support likely industrial animal factories is ideal.
Of course you'll get some people who believe all humans should die rather than use medicine or medical research, but in my experience that's just a loud and very small minority. Even PETA talks about and supports the necessity of medicine, though they aggressively push for better treatment of the animals and research to end the necessity in the first place.
There's still an uncomfortable amount of people on r/vegan saying people should just die because we shouldn't be killing pigs anyway.
Hell I just saw someone saying they'd let their own mother die.
Any number is an uncomfortable number, imo, but I do honestly think they're still in the (very vocal) small minority of vegans. I study and do work with animal law IRL and some activism on the side and, if it's any consolation, I've literally never met a vegan like that in real life. And I know a lot of vegans relatively speaking lol doesn't mean they aren't out there, but internet gives everyone* a platform, so I think we see them take their chances yelling into the void on here.
*At every age. I've gotten into debates on here before realizing the person I'm talking to is like...12...so however smart just doesn't have the life experience yet, ya know? At least for me, life seemed way more black and white and simple until I was out of my parents' house for a few years. And purely anecdotally, but the vegans on here who have been more black and white all or nothing no nuance have often been much younger and/or very new to the concept of veganism (with all the newly found enraged passion that brings) with the odd outlier here and there. Just my take, of course, but I wouldn't worry much about the "let everyone including my mother die" crowd.
Well, probably the same as they do about all modern medicine. They denounce it all, because it's all tested on animals. /s
Damn... That's one first I would not want to be before during or after lol
That being said, I hope this man lives a strong normal life and it changes the outcome for lord knows how many folks
My dad has a bovine valve.
I’m Jim Haggerty, and I’m porkin’ across America
Fun fact: This same gene editing technology that creates pig parts that won’t be rejected by humans also resulted in pork that can be eaten by people allergic to red meat.
Google “alpha gal”.
Any update on this? Is he still alive and what’s the quality of life?
My pops had to get a pig heart valve put into him to replace his which is kinda cool.
I smell bacon
Half PIG HALF MAN JERRY!
GMO pigs with human DNA so the body doesn’t reject? sounds like science fiction
Southpark's honey boo boo skit came true. IM GETTING A PIIIG HEEEAAART
He looks pissed that he survived that surgery
My heart is sweeter than bacon, child.
"Moshe, Moshe, wake up! We got good news ... and bad news."
I read a book in primary school called 'Pig Heart Boy' and this kid got the transplant and vegans threw pig blood at him, mad
Whaaaaaaaaaaaaaaa.......
immediately opens Audible
So I have a question. If you were trapped with him on a mountain, starving, and he died, would you be a cannibal if all you ate was his heart?
Asking for a friend.
Aaaaaand apparently he violently stabbed a man in the late 80’s and left the dude paralyzed for life.
I wouldn't get a pig heart in a facility that didn't have proper securement dressings for their NG tubes.....
They wouldn't tell you before the operation.
Science is amazing.
Was the pig genetically modified in some way to be more compatible with a human?
When he ends up morphing into that guy from the scene in "The Shining" nobody has the right to say anything🙄🤣
David most certainly looks like the “ehh fuck it” kinda dude. Lol
christina yang somewhere in awe
It's also the first successful condom nose transplant.
Who the fuck taped that NGT???
The ethics of a second chance: Pig heart transplant recipient stabbed a man seven times years ago
https://www.washingtonpost.com/dc-md-va/2022/01/13/pig-heart-transplant-stabbing-david-bennett/
Rip dave
Finally something Jews and Muslims can both hate - non-halal/non-kosher hearts
It’s disturbing, not sure how to feel towards it to be honest.
I can't speak for Halal, but Kosher refers specifically to consumption. You're not eating the heart...
The guy really wanted to die tho
Hope he said "oink" when walking up.
We're getting closer to having a Man Bear Pig. Al Gore warened is this can happen!
It’s all fine and well until the neighborhood children find out and start chanting “Pigheart” everytime they see you.
He's gonna have to change his last name to Bacon 😏
Great. Let's keep Boomers alive longer so they can suck more money out of the system. I was just saying the other day how I hope Boomers could find a way to rack up more debt they won't repay.
Lemme guess, he’s a cop?
This is impossible. Cops don’t have hearts.
First thing I thought of was improving the scarcity of available healthy transplant organs including hearts. Honestly it’s a freaky thought but what it medically entails seems to be great, including the amounts of bacon leftover 🥓 which I’m ok with lol
A family friend got his heart replaced by a pigs heart, also in Maryland. Interesting to see on here
Maybe they got a heart valve from a pig? That has been done for years, but I believe this is the very first whole pig heart to human transplant ever.
The Muslim world is queuing up for this!
Hope he's not vegan.
Amazing. He must be on 10 pounds of anti biotics
First one done in America but our system sucks, right?
All the humans: “YEAH!” All the pigs: “oh god no!”
and that's only the beginning.